A protocol for the in vitro selection of specific oligonucleotide probes for high-resolution DNA typing
The confident discrimination of nucleic acids that share a high degree of sequence identity is the major obstacle for the widespread applicability of multiplex DNA-based techniques. This diagnostic uncertainty originates in the insufficient specificity of hybridization, allowing cross-hybridization between unwanted probe?target combinations. Starting from a
AFP - At least 18 people were killed and 22 injured on Saturday when dozens of homes in northern Cairo collapsed after being hit by a massive rockslide, Egyptian emergency services said.