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A protocol for the in vitro selection of specific oligonucleotide probes for high-resolution DNA typing




The confident discrimination of nucleic acids that share a high degree of sequence identity is the major obstacle for the widespread applicability of multiplex DNA-based techniques. This diagnostic uncertainty originates in the insufficient specificity of hybridization, allowing cross-hybridization between unwanted probe?target combinations. Starting from a


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At least 18 dead in Cairo rockslide (AFP)

People search for survivors under the rubble of homes at the site of a massive rockslide at Moqattam hill in northern Cairo. At least 18 people were killed and 22 injured when dozens of homes collapsed after being hit by the rockslide, Egyptian emergency services said.(AFP/Khaled Desouki)AFP - At least 18 people were killed and 22 injured on Saturday when dozens of homes in northern Cairo collapsed after being hit by a massive rockslide, Egyptian emergency services said.



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