Silencing preBötzinger Complex somatostatin-expressing neurons induces persistent apnea in awake rat
Delineating neurons that underlie complex behaviors is of fundamental interest. Using adeno-associated virus 2, we expressed the Drosophila allatostatin receptor in somatostatin (Sst)-expressing neurons in the preBötzinger Complex (preBötC). Rapid silencing of these neurons in awake rats induced a persistent apnea without any respiratory movements to rescue their breathing. We hypothesize that breathing requires preBötC Sst neurons and that their sudden depression can lead to serious, even fatal, respiratory failure.
Barack Obama said his plan to end the Iraq war was unchanged and he was puzzled by the sharp reaction to his statement that he might "refine" his timetable for withdrawing U.S. combat troops.
AFP - The United States military wanted to test deadly nerve gases on Australian troops in a remote area of far north Queensland in the 1960s but Canberra refused, a report said Sunday.
