Articles and News for Jul08
  1. AILUN: reannotating gene expression data automatically

  2. ALEXA: a microarray design platform for alternative expression analysis

  3. A gene expression bar code for microarray data

  4. A map for fly explorers

  5. A meta-network of -omics

  6. A monoclonal antibody for G protein?coupled receptor crystallography

  7. A mouse with two mothers

  8. A practical guide to single-molecule FRET

  9. A probability-based approach for the analysis of large-scale RNAi screens

  10. A 'rough guide' to publication

  11. A secreted luciferase for ex vivo monitoring of in vivo processes

  12. Action shots of the nuclear pore complex

  13. Activity-based protein profiling for the functional annotation of enzymes

  14. Advancing forensics with precise target excision: the CellCut Plus laser microdissection instrument

  15. Amplifying the ancients

  16. An FKBP destabilization domain modulates protein levels in Plasmodium falciparum

  17. An HSV vector system for selection of ligand-gated ion channel modulators

  18. An activity-independent selection system of thermostable protein variants

  19. An evaluation of 3C-based methods to capture DNA interactions

  20. An experimental correction for arginine-to-proline conversion artifacts in SILAC-based quantitative proteomics

  21. An intelligently designed response

  22. An origami chip of DNA

  23. Analysis and validation of proteomic data generated by tandem mass spectrometry

  24. Another handle for RNA

  25. BAC to the future: functional genomics in mammals

  26. Bright far-red fluorescent protein for whole-body imaging

  27. Bringing bioluminescence into the picture

  28. Byte-ing off more than you can chew

  29. Caged compounds: photorelease technology for control of cellular chemistry and physiology

  30. Calcium imaging in a FlAsH

  31. ChIP-chip put to the test

  32. ChIP-seq: welcome to the new frontier

  33. Channeling the worm: microfluidic devices for nematode neurobiology

  34. Chemical biology: New electrophilic probes slide in

  35. Compare and conquer

  36. Controlling cells with light

  37. CultiFlask 50: a versatile tool for media optimization in biopharmaceutical production

  38. Cyclic nucleotide analogs as probes of signaling pathways

  39. DNA synthesis lights up

  40. Decoding protein modifications using top-down mass spectrometry

  41. Designer modulators

  42. Direct selection of human genomic loci by microarray hybridization

  43. Disaccharide structure code for the easy representation of constituent oligosaccharides from glycosaminoglycans

  44. Dissecting protein structure and function using directed evolution

  45. Do-it-yourself guide: how to use the modern single-molecule toolkit

  46. Engineering tumors with 3D scaffolds

  47. Engineers meet small RNA

  48. Enrichment of super-sized resequencing targets from the human genome

  49. Epitope tagging of endogenous proteins for genome-wide ChIP-chip studies

  50. Erratum: Deciphering the combinatorial histone code

  51. Erratum: Eukaryotic ribosome display with in situ DNA recovery

  52. Expanding the toolbox for remote control of neuronal circuits

  53. Experimental challenge to a 'rigorous' BRET analysis of GPCR oligomerization

  54. Experimental micro-matchmaking

  55. Fine-tuning RNAi in vivo

  56. Fish fingers on the menu

  57. Fission yeast goes synthetic

  58. FlAsHing the neighbors

  59. Fluorescence-force spectroscopy: watch your tether

  60. Focus on mass spectrometry in proteomics

  61. Follow the ubiquitin

  62. From structure to function

  63. GFP fails to inhibit actin-myosin interactions in vitro

  64. Gathering a bouquet of miRNA targets

  65. Gene expression in the worm

  66. Genetic control of neuronal activity in mice conditionally expressing TRPV1

  67. Genome-wide prediction of matrix attachment regions that increase gene expression in mammalian cells

  68. Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing

  69. HTRF® KinEASE? TK: a new solution for tyrosine kinase screening

  70. Harnessing mismatch repair to model sporadic cancers

  71. Hide and seek with cysteines

  72. High-density mapping of single-molecule trajectories with photoactivated localization microscopy

  73. Higher-energy C-trap dissociation for peptide modification analysis

  74. Highly efficient somatic-mutation identification using Escherichia coli mismatch-repair detection

  75. Highly inclined thin illumination enables clear single-molecule imaging in cells

  76. High-throughput cloning and expression in recalcitrant bacteria

  77. High-throughput genetic interaction mapping in the fission yeast Schizosaccharomyces pombe

  78. How the sum of its parts gets greater than the whole

  79. Hunting for ion channel modulators with herpes simplex virus

  80. Hunting hidden transcripts

  81. Illuminating aggregate heterogeneity in neurodegenerative disease

  82. Improved genetic manipulation of human embryonic stem cells

  83. In situ proteolysis for protein crystallization and structure determination

  84. In vitro whole-organ imaging: 4D quantification of growing mouse limb buds

  85. In vivo gene regulation in Salmonella spp. by a salicylate-dependent control circuit

  86. Incredible shrinking optics

  87. Induced pluripotency in human cells

  88. Inner glow

  89. Insulating gene expression

  90. Interaction in solution

  91. Iodoacetamide-induced artifact mimics ubiquitination in mass spectrometry

  92. Isoform discovery by targeted cloning, 'deep-well' pooling and parallel sequencing

  93. Keeping tabs on fluorescent tags

  94. Knockouts with a touch of a zinc finger

  95. Label-free continuous enzyme assays with macrocycle-fluorescent dye complexes

  96. Levers and fulcrums: progress in cis-regulatory motif models

  97. Life from information

  98. Lifeact: a versatile marker to visualize F-actin

  99. Live-cell map quest

  100. Living droplets

  101. Low- to high-throughput analysis of telomerase modulators with Telospot

  102. Luciferase-YFP fusion tag with enhanced emission for single-cell luminescence imaging

  103. MALDI imaging mass spectrometry: molecular snapshots of biochemical systems

  104. MAPAS: a tool for predicting membrane-contacting protein surfaces

  105. Mapping protein post-translational modifications with mass spectrometry

  106. Mapping the Arabidopsis proteome

  107. Mapping the plant methylome

  108. Mass spectrometry?based functional proteomics: from molecular machines to protein networks

  109. Matrix and Steiner-triple-system smart pooling assays for high-performance transcription regulatory network mapping

  110. MegaPlex PCR: a strategy for multiplex amplification

  111. Metastasis: two assays explore the two roads traveled

  112. Method of the Year

  113. MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells

  114. Microarray-based genomic selection for high-throughput resequencing

  115. Microfluidics and a garden hose

  116. Microfluidics for in vivo imaging of neuronal and behavioral activity in Caenorhabditis elegans

  117. Microfluidics: in search of a killer application

  118. Microfluidics: streamlining discovery in worm biology

  119. Mind the technology gap

  120. Monovalent, reduced-size quantum dots for imaging receptors on living cells

  121. Motionless fast 3D scanning

  122. Multiplex amplification of large sets of human exons

  123. ?N-GFP: an RNA reporter system for live-cell imaging

  124. Neglected diagnostics

  125. NetworKIN in context?casting a net for kinases

  126. Networking an organism

  127. New lasers for flow cytometry: filling the gaps

  128. News in brief

  129. Next-generation sequencing transforms today's biology

  130. No faulty-gene carrier need apply

  131. Npro fusion technology to produce proteins with authentic N termini in E. coli

  132. Of very young mice and men

  133. PCR's next frontier

  134. Pathogens on aspirin: promising research and therapeutic applications

  135. Pitfalls of measuring feeding rate in the fruit fly Drosophila melanogaster

  136. Plasmid-chromosome shuffling for non-deletion alleles in yeast

  137. Pony express to mitochondria

  138. Primer: Sequencing?the next generation

  139. Prion biology: the quest for the test

  140. Prion strain discrimination using luminescent conjugated polymers

  141. Protein crystallization: from purified protein to diffraction-quality crystal

  142. Protein engineers turned evolutionists

  143. Protein production and purification

  144. Protein structure determination... blindfolded

  145. Protein suicide highlights the cell cycle

  146. Proteomics from the clinical perspective: many hopes and much debate

  147. Putting a trace on metabolites

  148. Quantifying small numbers of antibodies with a 'near-universal' protein-DNA chimera

  149. Quantized plasmon quenching dips nanospectroscopy via plasmon resonance energy transfer

  150. RNA antibodies: upping the ante

  151. Rapamycin to the rescue!

  152. Rapid control of protein level in the apicomplexan Toxoplasma gondii

  153. Reannotation of array probes at NCBI's GEO database

  154. Red-shifted Renilla reniformis luciferase variants for imaging in living subjects

  155. Reply to: Experimental challenge to a 'rigorous' BRET analysis of GPCR oligomerization

  156. Reply to ?GFP fails to inhibit actin-myosin interactions in vitro?

  157. Reply to ?Pitfalls of measuring feeding rate in the fruit fly Drosophila melanogaster?

  158. Research in situ

  159. Rewiring E. coli

  160. SNPing and chipping away at the fly genome

  161. SNPs matter: impact on detection of differential expression

  162. STED microscopy with continuous wave beams

  163. Securing accuracy and precision when pipetting hot and cold liquids with Microman®

  164. Seeing fluorescence at super-resolution

  165. Semi-supervised learning for peptide identification from shotgun proteomics datasets

  166. Sequence census methods for functional genomics

  167. Simplified ultrasensitive prion detection by recombinant PrP conversion with shaking

  168. Single-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopy

  169. Smaller can be better

  170. Snapshots of mouse development

  171. Soaking up small RNAs

  172. Solution NMR of supramolecular complexes: providing new insights into function

  173. Speed-mapping quantitative trait loci using microarrays

  174. Standardizing proteomics

  175. Stem and iPS cell selection: quantitation of surface marker (SSEA1) and intracellular GFP

  176. Structural analysis of macromolecular assemblies

  177. Structural genomics: from genes to structures with valuable materials and many questions in between

  178. Structural genomics in the spotlight

  179. Sugars direct stem cell homing

  180. Super-resolution for a 3D world

  181. Super-resolution light microscopy goes live

  182. Suspended-drop electroporation for high-throughput delivery of biomolecules into cells

  183. Switching genes off?all the way

  184. Switching parasite proteins on and off

  185. Talking points

  186. The Bionas® system bridges the gap between in vivo and in vitro

  187. The beginning of the end for microarrays?

  188. The living brain, unlabeled

  189. The new fluorescent probes on the block

  190. The protein microscope: incorporating mass spectrometry into cell biology

  191. The secret of NIMS

  192. The smaller the better

  193. The year of sequencing

  194. There is a virus going around

  195. Thou shalt share your data

  196. Three-dimensional preparation and imaging reveal intrinsic microtubule properties

  197. Tomographic phase microscopy

  198. Top-down mass spectrometry

  199. Tractable Cre-lox system for stochastic alteration of genes in mice

  200. Training a computer's eye on cell shape

  201. Transcription factors come to call

  202. Transgenesis via permanent integration of genes in repopulating spermatogonial cells in vivo

  203. Tuning in to flower power

  204. Turning fluorescent proteins into energy-saving light bulbs

  205. Two pictures are better than one

  206. Two-photon dual-color imaging using fluorescent proteins

  207. Ultrasensitive detection of scrapie prion protein using seeded conversion of recombinant prion protein

  208. Unexpected failure rates for modular assembly of engineered zinc fingers

  209. Using expression profiling data to identify human microRNA targets

  210. Variations on atomic force microscopy

  211. Vector-free DNA constructs improve transgene expression in C. elegans

  212. Viral checkmate

  213. Visualizing single DNA-bound proteins using DNA as a scanning probe

  214. Watching single molecules in cells

  215. What ID is, beyond what it is not

  216. When microRNAs activate translation

  217. Whispering-gallery-mode biosensing: label-free detection down to single molecules

  218. Whole genome?amplified DNA: insights and imputation

  219. YFP photoconversion revisited: confirmation of the CFP-like species

    220. Find this article in Google