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A gene expression bar code for microarray data




The ability to measure genome-wide expression holds great promise for characterizing cells and distinguishing diseased from normal tissues. Thus far, microarray technology has been useful only for measuring relative expression between two or more samples, which has handicapped its ability to classify tissue types. Here we present a method that can successfully predict tissue type based on data from a single hybridization. A preliminary web-tool is available online (http://rafalab.jhsph.edu/barcode/).


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A Plague of Rats Isnt Worth Some Ink? Bangladesh Is in Crisis

Spent much time thinking about Bangladesh lately? If the answer is no, don't worry — I was in the same boat, so to speak, until I saw these pictures.

Earlier this month, crushing rains left 20 people dead and over 20,000 stranded when overwhelming rainfall left five feet of standing water in the low-lying areas. This is on top of already taxed landscapes that flooded when melting Himalayan glaciers burst the 200 rivers that web across the country last year. Bangladesh under water is seeming like a real and permanent possibility.

The International Panel on Climate Change (IPCC) — whose claims are usually conservative — said that Bangladesh is heading to lose 17 percent of its land and 30 percent of its food production by 2050. That's like California and New York drowning, and the whole Midwest ceasing production of food.


If this happens, more than 20 million Bangladeshis will be without a patch of land to stand on. Though hardship in the country isn't entirely recent: since 1971, Bangladesh has endured over 200 disasters that have left a total of 500,000 dead and affected a total of 500 million people.

And I haven't even said anything about the plague of rats that's consuming all of their food. A plague of rats. I wish, wish there was more room for stories like this in the general consciousness — shouldn't we be hearing about this every night? Not to dwell on the gloomy, but just knowing about this makes the answer to this question pretty clear to me.

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Polish prosecutors probe possible CIA jail (Reuters)

A guard shuts the gate to the airport in Szymany in northeastern Poland in this file 2005 picture. Human Rights Watch identified the airport as a potential site of alleged CIA prisons used to interrogate al Qaeda captives. Poland strongly denied it was hosting such facilities. (FORUM/Tomasz Marek/Reuters)Reuters - The Polish prosecutor's office is investigating allegations that there was a CIA prison in Poland where al Qaeda suspects were questioned and guards might have used methods close to torture, the prime minister's top adviser said on Friday.



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