Articles and News for Jul08

  1. A catch to integrin activation

  2. A critical function for TGF-? signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells

  3. A dominant function for interleukin 27 in generating interleukin 10?producing anti-inflammatory T cells

  4. A hornet's nest for $1,000

  5. A new player in lymphocyte homing

  6. Activated leukocyte cell adhesion molecule promotes leukocyte trafficking into the central nervous system

  7. Acute upregulation of an NKG2D ligand promotes rapid reorganization of a local immune compartment with pleiotropic effects on carcinogenesis

  8. Akirins are highly conserved nuclear proteins required for NF-?B-dependent gene expression in drosophila and mice

  9. Akirins versus infection

  10. An autonomous CDR3? is sufficient for recognition of the nonclassical MHC class I molecules T10 and T22 by ?? T cells

  11. Antigen receptor diversification and chromosome translocations

  12. Antigen receptor signaling: the Tuscan connection

  13. Antigens take the shuttle

  14. Arresting autoimmunity by blocking ?-arrestin 1

  15. Assessing the status of human immunology

  16. Association between the Igk and Igh immunoglobulin loci mediated by the 3? Igk enhancer induces 'decontraction' of the Igh locus in pre?B cells

  17. Autoimmunity and transplantation: a meeting at the crossroads in Berlin

  18. Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs

  19. Bacterial cell walls, innate immunity and immunoadjuvants

  20. Basophils enhance immunological memory responses

  21. Basophils: in the spotlight at last

  22. Basophils now enhance memory

  23. Bring out your dead

  24. CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entry-independent mechanisms

  25. CCR5 and its ligands: a new axis of evil?

  26. CD160 and BTLA: LIGHTs out for CD4+ T cells

  27. CD160 inhibits activation of human CD4+ T cells through interaction with herpesvirus entry mediator

  28. CD19 is essential for B cell activation by promoting B cell receptor?antigen microcluster formation in response to membrane-bound ligand

  29. CD3 ITAMs count!

  30. CD3?: PeRuSing for positive selection

  31. CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation?mediated apoptosis of effector CD4+ T cells

  32. CD8+ T cells are kept in tune by modulating IL-7 responsiveness

  33. COP9 signalosome subunit 8 is essential for peripheral T cell homeostasis and antigen receptor?induced entry into the cell cycle from quiescence

  34. Catecholaminergic neurotransmitters regulate migration and repopulation of immature human CD34+ cells through Wnt signaling

  35. Celebrating great ideas

  36. Competition for cytokines: Treg cells take all

  37. Connecting immunology research to public health: Cuban biotechnology

  38. Construction and destruction of MHC class I in the peptide-loading complex

  39. 'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR

  40. Corrigendum: Comprehensive epigenetic profiling identifies multiple distal regulatory elements directing transcription of the gene encoding interferon-?

  41. Corrigendum: Ligand-induced conformational changes allosterically activate Toll-like receptor 9

  42. Corrigendum: Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes

  43. Corrigendum: Regulation of naive T cell function by the NF-?B pathway

  44. Corrigendum: The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways

  45. Corrigendum: The clonal selection theory: 50 years since the revolution

  46. Critical regulation of CD4+ T cell survival and autoimmunity by ?-arrestin 1

  47. Cross-presentation: avoiding trafficking chaos?

  48. Crystal structure of the IL-15?IL-15R? complex, a cytokine-receptor unit presented in trans

  49. Cytoplasmic double-stranded DNA sensor

  50. Defective mast cell effector functions in mice lacking the CRACM1 pore subunit of store-operated calcium release?activated calcium channels

  51. Dendritic cell genealogy: a new stem or just another branch?

  52. Development, cytokine profile and function of human interleukin 17?producing helper T cells

  53. Development of plasmacytoid and conventional dendritic cell subtypes from single precursor cells derived in vitro and in vivo

  54. Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death

  55. Differentiation of human TH-17 cells does require TGF-?!

  56. Direct priming of antiviral CD8+ T cells in the peripheral interfollicular region of lymph nodes

  57. Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance

  58. Dynamic imaging of chemokine-dependent CD8+ T cell help for CD8+ T cell responses

  59. Dynamics of host defense: the view at the front lines

  60. Edward A. Boyse 1923?2007

  61. Epitope-specific regulation: the elephant in the bathtub

  62. Erg in stem cells: a function emerges

  63. Erratum: Epigenetic regulation of Ifng expression

  64. Erratum: Pathogen subversion of cell-intrinsic innate immunity

  65. Essential function for SWI-SNF chromatin-remodeling complexes in the promoter-directed assembly of Tcrb genes

  66. Essential function for the calcium sensor STIM1 in mast cell activation and anaphylactic responses

  67. Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells

  68. Finally, MALT1 is a protease!

  69. Finding a way out: lymphocyte egress from lymphoid organs

  70. 'Fine tuning' TLR signaling

  71. Follicular shuttling of marginal zone B cells facilitates antigen transport

  72. Foxo1 directly regulates the transcription of recombination-activating genes during B cell development

  73. Foxos around make B cells tolerable

  74. From influenza to HIV?and back?

  75. Functions of natural killer cells

  76. Genotoxic stress regulates expression of the proto-oncogene Bcl6 in germinal center B cells

  77. Germline-encoded recognition of diverse glycolipids by natural killer T cells

  78. Global health science: a threat and an opportunity for collaborative clinical science

  79. Global scourge

  80. HIV's gut feeling

  81. Holding antigen where B cells can find it

  82. Homeostasis of dendritic cell pool in lymphoid organs

  83. How T cells 'find' the right dendritic cell

  84. IL-10 or not IL-10: that is the question

  85. IL-17 drives germinal center B cells?

  86. IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

  87. IRAK2 takes its place in TLR signaling

  88. IRF1: a deus ex machina in TH1 differentiation

  89. Identification of clonogenic common Flt3+M-CSFR+ plasmacytoid and conventional dendritic cell progenitors in mouse bone marrow

  90. Immune responses to commensal and environmental microbes

  91. Immunity to malaria: more questions than answers

  92. Immunological outreach through positive selection

  93. Immunology around the world

  94. Immunology in China: the past, present and future

  95. Immunology in natura: clinical, epidemiological and evolutionary genetics of infectious diseases

  96. Immunology in the Arabian desert

  97. Immunopathology of highly virulent pathogens: insights from Ebola virus

  98. In vivo veritas: pathogenesis of infection as it actually happens

  99. Inhibitory receptors: whose side are they on?

  100. Innocents abroad: regulating where naive T cells go

  101. Interleukin 15?mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1

  102. Interleukin 17?producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice

  103. Interleukins 1? and 6 but not transforming growth factor-? are essential for the differentiation of interleukin 17?producing human T helper cells

  104. Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10

  105. Itching to end NF-?B

  106. Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17?producing T cell responses

  107. Location, location, location: identifying the neighborhoods of LPS signaling

  108. Lymph node chemokines promote sustained T lymphocyte motility without triggering stable integrin adhesiveness in the absence of shear forces

  109. Lymphocyte transmigration in the brain: a new way of thinking

  110. MALT1 directs B cell receptor?induced canonical nuclear factor-?B signaling selectively to the c-Rel subunit

  111. Macrophage tolerance: CD47?SIRP-??mediated signals matter

  112. Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3

  113. Mast cell?derived interleukin 10 limits skin pathology in contact dermatitis and chronic irradiation with ultraviolet B

  114. Mentoring and networking: how to make it work

  115. Metchnikoff's Legacy in 2008

  116. Minimal activation of memory CD8+ T cell by tissue-derived dendritic cells favors the stimulation of naive CD8+ T cells

  117. Mistaken notions about natural killer cells

  118. Moving out: mobilizing activated T cells from lymphoid tissues

  119. Multiple sclerosis: a complicated picture of autoimmunity

  120. NKG2D signaling is coupled to the interleukin 15 receptor signaling pathway

  121. Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor

  122. Natural killer cell?directed therapies: moving from unexpected results to successful strategies

  123. New dimensions of CIITA

  124. New niches for B cells

  125. No DL1 Notch ligand? GATA be a mast cell

  126. Nuclear geography and allelic exclusion

  127. Of lineage and legacy: the development of mammalian hematopoietic stem cells

  128. One cell?one antibody: prelude and aftermath

  129. Outside the box

  130. Oxidative burst without phagocytes: the role of respiratory proteins

  131. PTEN gives neutrophils direction

  132. Pathogen subversion of cell-intrinsic innate immunity

  133. Pathogenesis: how far have we come?

  134. Paul J. Leibson 1952?2007

  135. Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes

  136. Politicizing science no more

  137. Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells

  138. Post-transcriptional control of cytokine production

  139. Prelude to a good story

  140. Probing the 'labyrinth' linking the innate and adaptive immune systems

  141. Promoting peace through science

  142. Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic

  143. Protein-glycan interactions in the control of innate and adaptive immune responses

  144. P-selectin primes leukocyte integrin activation during inflammation

  145. Pushing the limits

  146. Recent advances in antigen processing and presentation

  147. Redox regulation of peptide receptivity of major histocompatibility complex class I molecules by ERp57 and tapasin

  148. Regula'ten' the gut

  149. Regulation of T cell survival through coronin-1?mediated generation of inositol-1,4,5-trisphosphate and calcium mobilization after T cell receptor triggering

  150. Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3? precursor cells in the absence of interleukin 10

  151. Reply to ?TSLP-mediated fetal B lymphopoiesis??

  152. Research Highlights

  153. Respiratory protein?generated reactive oxygen species as an antimicrobial strategy

  154. 'Role reversal' for the receptor PAR1 in sepsis-induced vascular damage

  155. Rsk Tolls the bell for endocytosis in DCs

  156. SLP-65 regulates immunoglobulin light chain gene recombination through the PI(3)K-PKB-Foxo pathway

  157. SWI-SNF: promoter of accessibility

  158. Scalable signaling mediated by T cell antigen receptor?CD3 ITAMs ensures effective negative selection and prevents autoimmunity

  159. Science in an open society

  160. Science, medicine and research in the developing world: a perspective

  161. Selective loading of high-affinity peptides onto major histocompatibility complex class I molecules by the tapasin-ERp57 heterodimer

  162. Semaphorins and their receptors in immune cell interactions

  163. Sequential control of Toll-like receptor?dependent responses by IRAK1 and IRAK2

  164. Sir Frank Macfarlane Burnet 1899?1985

  165. Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer

  166. Stepping up to the plate

  167. Stress gets under your skin

  168. Structural evidence for a germline-encoded T cell receptor?major histocompatibility complex interaction 'codon'

  169. Structure of and influence of a tick complement inhibitor on human complement component 5

  170. Subcapsular encounter and complement-dependent transport of immune complexes by lymph node B cells

  171. Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27?stimulated T cells

  172. Suppression of immunoglobulin E?mediated allergic responses by regulator of G protein signaling 13

  173. TH-17 differentiation: of mice and men

  174. TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-?

  175. TRIM-ing down Tolls

  176. TSLP-mediated fetal B lymphopoiesis?

  177. T cell antigen receptor stimulation induces MALT1 paracaspase?mediated cleavage of the NF-?B inhibitor A20

  178. T cell heterogeneity: firmly fixed, predominantly plastic or merely malleable?

  179. T cell receptors get back to basics

  180. T helper type 2 differentiation and intracellular trafficking of the interleukin 4 receptor-? subunit controlled by the Rac activator Dock2

  181. The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20

  182. The E3 ubiquitin ligase Itch regulates expression of transcription factor Foxp3 and airway inflammation by enhancing the function of transcription factor TIEG1

  183. The Foxp3+ regulatory T cell: a jack of all trades, master of regulation

  184. The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways

  185. The clonal selection theory: 50 years since the revolution

  186. The contribution of transcription factor IRF1 to the interferon-??interleukin 12 signaling axis and TH1 versus TH-17 differentiation of CD4+ T cells

  187. The cysteinyl leukotrienes: Where do they come from? What are they? Where are they going?

  188. The development of inflammatory TH-17 cells requires interferon-regulatory factor 4

  189. The habitual, diverse and surmountable obstacles to human immunology research

  190. The proteolytic activity of the paracaspase MALT1 is key in T cell activation

  191. The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics

  192. Through the Signaling Gateway

  193. Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5

  194. 'Tuning' of type I interferon?induced Jak-STAT1 signaling by calcium-dependent kinases in macrophages

  195. Two in one: dual function of an invertebrate antigen receptor

  196. Unexpected partnership between IL-15 and DAP10

  197. Unique functions of the type II interleukin 4 receptor identified in mice lacking the interleukin 13 receptor ?1 chain

  198. Up on the tightrope: natural killer cell activation and inhibition

  199. Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction

  200. What turns on Foxp3?

  201. Find this article in Google