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Conflicting evidence on the frequency of ESR1 amplification in breast cancer




An earlier report of high-frequency ESR1 amplification in breast cancer is now challenged by correspondence from four groups. This discussion of whether or not there is something 'FISHy' about ESR1 amplification highlights the difficulty of validating such observations, leaving the frequency and clinical significance of ESR1 amplification in breast cancer an open question.


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At least 18 dead in Cairo rockslide (AFP)

People search for survivors under the rubble of homes at the site of a massive rockslide at Moqattam hill in northern Cairo. At least 18 people were killed and 22 injured when dozens of homes collapsed after being hit by the rockslide, Egyptian emergency services said.(AFP/Khaled Desouki)AFP - At least 18 people were killed and 22 injured on Saturday when dozens of homes in northern Cairo collapsed after being hit by a massive rockslide, Egyptian emergency services said.



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