Articles and News for Aug08

  1. ?1 Integrin deletion from the basal compartment of the mammary epithelium affects stem cells

  2. AK2 activates a novel apoptotic pathway through formation of a complex with FADD and caspase-10

  3. AKR2A-mediated import of chloroplast outer membrane proteins is essential for chloroplast biogenesis

  4. ARF1 is directly involved in dynamin-independent endocytosis

  5. A TAG1-APP signalling pathway through Fe65 negatively modulates neurogenesis

  6. A ?-catenin gradient links the clock and wavefront systems in mouse embryo segmentation

  7. A concentration-dependent switch in the bacterial response to temperature

  8. A core Klf circuitry regulates self-renewal of embryonic stem cells

  9. A crucial role of a high mobility group protein HMGA2 in cardiogenesis

  10. A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment

  11. A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-? transactivation

  12. A not-so-rough guide to genes and cloning

  13. A pathway for phagosome maturation during engulfment of apoptotic cells

  14. A proteomic screen reveals SCFGrr1 targets that regulate the glycolytic?gluconeogenic switch

  15. A reciprocal tensin-3?cten switch mediates EGF-driven mammary cell migration

  16. A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis

  17. A traffic-activated Golgi-based signalling circuit coordinates the secretory pathway

  18. Actin nucleation: bacteria get in-Spired

  19. Actin restricts Fc?RI diffusion and facilitates antigen-induced receptor immobilization

  20. Addendum

  21. Akt phosphorylation regulates the tumour-suppressor merlin through ubiquitination and degradation

  22. All good cells come from cells

  23. An agonist-induced conformational change in the growth hormone receptor determines the choice of signalling pathway

  24. Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell?cell and cell?matrix contacts

  25. Architectural dynamics of the meiotic spindle revealed by single-fluorophore imaging

  26. Arf6 and microtubules in adhesion-dependent trafficking of lipid rafts

  27. Arsenic degrades PML or PML?RAR? through a SUMO-triggered RNF4/ubiquitin-mediated pathway

  28. Autophagosome formation: core machinery and adaptations

  29. BRCA1 and stem cells: tumour typecasting

  30. Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking

  31. Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis

  32. Breaking down EMT

  33. Cables links Robo-bound Abl kinase to N-cadherin-bound ?-catenin to mediate Slit-induced modulation of adhesion and transcription

  34. Cathepsin L activity controls adipogenesis and glucose tolerance

  35. Cdh1: a master G0/G1 regulator

  36. Celebrity cells

  37. Cell fate in the Hand of Plk4

  38. Cell polarity in development and cancer

  39. Changing gear

  40. Cilia put a brake on Wnt signalling

  41. Control of HIPK2 stability by ubiquitin ligase Siah-1 and checkpoint kinases ATM and ATR

  42. Control of daughter centriole formation by the pericentriolar material

  43. Convergent extension and the hexahedral cell

  44. Correlated three-dimensional light and electron microscopy reveals transformation of mitochondria during apoptosis

  45. Corrigendum

  46. Coupling of cortical dynein and G? proteins mediates spindle positioning in Caenorhabditis elegans

  47. Dam1 complexes go it alone on disassembling microtubules

  48. Debugging cellular reprogramming

  49. Developing disease

  50. Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II

  51. Differential function of Tie2 at cell?cell contacts and cell?substratum contacts regulated by angiopoietin-1

  52. Differentially oriented populations of actin filaments generated in lamellipodia collaborate in pushing and pausing at the cell front

  53. Differentiation plasticity regulated by TGF-? family proteins in development and disease

  54. Direct regulation of TWIST by HIF-1? promotes metastasis

  55. Disruption of KIF17?Mint1 interaction by CaMKII-dependent phosphorylation: a molecular model of kinesin?cargo release

  56. EB1 regulates microtubule dynamics and tubulin sheet closure in vitro

  57. EGFR signalling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer

  58. ERK and MDM2 prey on FOXO3a

  59. ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

  60. Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5

  61. Entosis: cell death by invasion

  62. Enucleation of cultured mouse fetal erythroblasts requires Rac GTPases and mDia2

  63. EphrinB1 controls cell?cell junctions through the Par polarity complex

  64. Epidermal JunB represses G-CSF transcription and affects haematopoiesis and bone formation

  65. Epigenetic memory: H3.3 steps in the groove

  66. Epigenetic memory of an active gene state depends on histone H3.3 incorporation into chromatin in the absence of transcription

  67. Epithelial coating controls mesenchymal shape change through tissue-positioning effects and reduction of surface-minimizing tension

  68. Erratum

  69. Exocytotic catecholamine release is not associated with cation flux through channels in the vesicle membrane but Na+ influx through the fusion pore

  70. Extensive fusion of haematopoietic cells with Purkinje neurons in response to chronic inflammation

  71. Extra centrosomes and/or chromosomes prolong mitosis in human cells

  72. Facing up to Mena: Tes(ting) times for EVH1 domains

  73. Fat or bone? A non-canonical decision

  74. Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells

  75. Filopodia are required for cortical neurite initiation

  76. Filopodial actin bundles are not necessary for microtubule advance into the peripheral domain of Aplysia neuronal growth cones

  77. Focal adhesion kinase controls actin assembly via a FERM-mediated interaction with the Arp2/3 complex

  78. Found in translation

  79. Functional atlas of the integrin adhesome

  80. GAPDH and the search for alternative energy

  81. GEP100 links epidermal growth factor receptor signalling to Arf6 activation to induce breast cancer invasion

  82. Genetic control of single lumen formation in the zebrafish gut

  83. Genome-scale RNAi profiling of cell division in human tissue culture cells

  84. Genome-wide analysis identifies a general requirement for polarity proteins in endocytic traffic

  85. Genomic stability and tumour suppression by the APC/C cofactor Cdh1

  86. German science reinvigorated

  87. Getting invasive with GEP100 and Arf6

  88. Golgi gets wired up

  89. Good review

  90. Green light for chloroplast outer-membrane proteins

  91. Heads or tails: can Wnt tell which one is up?

  92. Holding back TOR advances mitosis

  93. How size is controlled: from Hippos to Yorkies

  94. HtrA2 and Parkinson's disease: think PINK?

  95. Human?animal cytoplasmic hybrid embryos, mitochondria, and an energetic debate

  96. IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade

  97. Inactivation of Cdh1 by synergistic action of Cdk1 and polo kinase is necessary for proper assembly of the mitotic spindle

  98. Inhibition of Arp2/3-mediated actin polymerization by PICK1 regulates neuronal morphology and AMPA receptor endocytosis

  99. Inhibition of Crm1?p53 interaction and nuclear export of p53 by poly(ADP-ribosyl)ation

  100. Inn1 couples contraction of the actomyosin ring to membrane ingression during cytokinesis in budding yeast

  101. Integrin-dependent anchoring of a stem-cell niche

  102. Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells

  103. Intra-axonal translation and retrograde trafficking of CREB promotes neuronal survival

  104. It takes guts to make a single lumen

  105. Kif3a constrains ?-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms

  106. Leading the charge

  107. Less is More

  108. Lipid droplets highjack SNAREs

  109. MUC1 oncoprotein activates the I?B kinase ? complex and constitutive NF-?B signalling

  110. Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease

  111. Melanopsin-dependent photo-perturbation reveals desynchronization underlying the singularity of mammalian circadian clocks

  112. Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission

  113. MesP1 drives vertebrate cardiovascular differentiation through Dkk-1-mediated blockade of Wnt-signalling

  114. Micromanaging metastasis

  115. Missing the boat: a loophole in start-up funding?

  116. Modulation of intracellular trafficking regulates cell intercalation in the Drosophila trachea

  117. Moesin stiffens up mitosis

  118. Motor-cargo release: CaMKII as a traffic cop

  119. Motor-free mitochondrial presequence translocase drives membrane integration of preproteins

  120. Much HUBbub about stem-cell niches

  121. Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion

  122. Myeloid and lymphoid contribution to non-haematopoietic lineages through irradiation-induced heterotypic cell fusion

  123. Nanoclusters digitize Ras signalling

  124. Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells

  125. Nanog maintains pluripotency of mouse embryonic stem cells by inhibiting NF?B and cooperating with Stat3

  126. Netrin-1 mediates neuronal survival through PIKE-L interaction with the dependence receptor UNC5B

  127. Network news: complete nuclear coverage

  128. Neural stem cells: guardians of the brain

  129. Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis

  130. Neurogenesis directed by Sirt1

  131. Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis

  132. Normal brain development in importin-?5 deficient-mice

  133. Nuclear envelope formation by chromatin-mediated reorganization of the endoplasmic reticulum

  134. Nucleolar release of Hand1 acts as a molecular switch to determine cell fate

  135. OS-9 and GRP94 deliver mutant ?1-antitrypsin to the Hrd1?SEL1L ubiquitin ligase complex for ERAD

  136. Of Mice and Men

  137. Opposing roles for glypicans in Hedgehog signalling

  138. Opposing roles for p16Ink4a and p19Arf in senescence and ageing caused by BubR1 insufficiency

  139. Osteogenic transcription factor Runx2 is a maternal determinant of dorsoventral patterning in zebrafish

  140. Outsourcing CREB translation to axons to survive

  141. PARtners for endocytosis

  142. PDK1 regulates cancer cell motility by antagonising inhibition of ROCK1 by RhoE

  143. PIM1 and MYC: a changing relationship?

  144. PIM1-dependent phosphorylation of histone H3 at serine 10 is required for MYC-dependent transcriptional activation and oncogenic transformation

  145. Patching the gaps in Hedgehog signalling

  146. Pax7 activates myogenic genes by recruitment of a histone methyltransferase complex

  147. Phosphoregulation and depolymerization-driven movement of the Dam1 complex do not require ring formation

  148. Phosphorylation of histone H3 at threonine 11 establishes a novel chromatin mark for transcriptional regulation

  149. Plasma membrane nanoswitches generate high-fidelity Ras signal transduction

  150. Polycomb response elements mediate the formation of chromosome higher-order structures in the bithorax complex

  151. Prometaphase APCcdh1 activity prevents non-disjunction in mammalian oocytes

  152. Protein arginine-methyltransferase-dependent oncogenesis

  153. RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

  154. Rapid activation of ATM on DNA flanking double-strand breaks

  155. Redox rescues virus from ER trap

  156. Registries and banks

  157. Regulated ATP release from astrocytes through lysosome exocytosis

  158. Regulation of TORC1 by Rag GTPases in nutrient response

  159. Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin

  160. Regulation of autophagy by cytoplasmic p53

  161. RhoA and microtubule dynamics control cell?basement membrane interaction in EMT during gastrulation

  162. Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells

  163. Ring around the genes

  164. Root growth in Arabidopsis requires gibberellin/DELLA signalling in the endodermis

  165. SIRT1 sumoylation regulates its deacetylase activity and cellular response to genotoxic stress

  166. SNARE proteins mediate fusion between cytosolic lipid droplets and are implicated in insulin sensitivity

  167. SNX4 coordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartment

  168. STIM1 signalling controls store-operated calcium entry required for development and contractile function in skeletal muscle

  169. STIM1 tracks growing microtubule ends

  170. Scaling the EU visa barrier

  171. Secrets of a killer

  172. Securin' M-phase entry

  173. Shaping membranes into autophagosomes

  174. Sirt1 contributes critically to the redox-dependent fate of neural progenitors

  175. Small RNAs tell big stories in Whistler

  176. S-nitrosylation of microtubule-associated protein 1B mediates nitric-oxide-induced axon retraction

  177. Sophistications of cell sorting

  178. Spatial regulation of Fus3 MAP kinase activity through a reaction-diffusion mechanism in yeast pheromone signalling

  179. Spindle-localized CPE-mediated translation controls meiotic chromosome segregation

  180. Spindles: one speckle at a time

  181. Sterol-dependent endocytosis mediates post-cytokinetic acquisition of PIN2 auxin efflux carrier polarity

  182. Successful grant fishing in funding droughts

  183. TAGing APP constrains neurogenesis

  184. TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal

  185. TBL1?TBLR1 and ?-catenin recruit each other to Wnt target-gene promoter for transcription activation and oncogenesis

  186. TOR signalling regulates mitotic commitment through the stress MAP kinase pathway and the Polo and Cdc2 kinases

  187. Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1

  188. Telomere lengthening early in development

  189. Telomeric RNA enters the game

  190. Tensile forces govern germ-layer organization in zebrafish

  191. Tensin relief facilitates migration

  192. The F-box protein Fbl10 is a novel transcriptional repressor of c-Jun

  193. The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein

  194. The NHL-domain protein Wech is crucial for the integrin?cytoskeleton link

  195. The Smc5?Smc6 complex and SUMO modification of Rad52 regulates recombinational repair at the ribosomal gene locus

  196. The auxin influx carrier LAX3 promotes lateral root emergence

  197. The lipid droplet is an important organelle for hepatitis C virus production

  198. The many faces of actin: matching assembly factors with cellular structures

  199. The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

  200. The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis

  201. The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1

  202. The mouse ascending: perspectives for human-disease models

  203. The regulated assembly of a PKC? complex controls the completion of cytokinesis

  204. The type I TGF-? receptor is covalently modified and regulated by sumoylation

  205. Thrilling transcription through threonine phosphorylation

  206. Toll-like receptors modulate adult hippocampal neurogenesis

  207. Turning to the cold

  208. UVRAG reveals its second nature

  209. Unified mode of centromeric protection by shugoshin in mammalian oocytes and somatic cells

  210. VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400

  211. WAVE and Arp2/3 jointly inhibit filopodium formation by entering into a complex with mDia2

  212. Walking the line: balancing work and family

  213. What to publish?

  214. Wingless secretion promotes and requires retromer-dependent cycling of Wntless

  215. Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex

  216. Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export

  217. elipsa is an early determinant of ciliogenesis that links the IFT particle to membrane-associated small GTPase Rab8

  218. p53-Driven apoptosis limits centrosome amplification and genomic instability downstream of NPM1 phosphorylation

  219. p53 regulates glucose metabolism through an IKK-NF-?B pathway and inhibits cell transformation

  220. Find this article in Google